{"product_id":"mots-c","title":"MOTS-C (Lyophilised)","description":"\u003cp\u003e\u003cstrong\u003eMOTS-C (Lyophilised)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct \u0026amp; Research Profile\u003c\/strong\u003e\u003cbr\u003eMOTS-C, short for Mitochondrial Open Reading Frame of the 12S rRNA type-c, is a 16-amino-acid mitochondrial-derived peptide encoded within a short open reading frame of mitochondrial DNA.\u003c\/p\u003e\n\u003cp\u003eUnlike conventional peptides encoded by nuclear genes, MOTS-C originates from the mitochondrial genome, giving it a distinctive role in research examining communication between mitochondria and the wider cell.\u003c\/p\u003e\n\u003cp\u003eLaboratory studies have investigated MOTS-C in relation to cellular energy regulation, mitochondrial stress responses and AMP-activated protein kinase (AMPK) signalling. Research has also examined its influence on folate and purine metabolic pathways, including mechanisms associated with intracellular AICAR accumulation and subsequent AMPK activation.\u003c\/p\u003e\n\u003cp\u003eUnder cellular stress conditions, MOTS-C has been investigated for its ability to relocate toward the nucleus and participate in regulation of stress-responsive gene expression. This mitochondrial-to-nuclear signalling behaviour makes it particularly relevant to research involving retrograde mitochondrial communication, metabolic regulation and cellular adaptation.\u003c\/p\u003e\n\u003cp\u003eIts defined mitochondrial origin and short peptide structure also make MOTS-C suitable for analytical characterisation, structure–activity studies, mitochondrial signalling research and comparative investigation alongside other mitochondrial-derived peptides.\u003c\/p\u003e\n\u003cp\u003eSupplied as a lyophilised powder in sealed laboratory vials, MOTS-C is available in 10mg, 20mg and 40mg quantities for research and analytical applications.\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003cstrong\u003e18+ Purchase Confirmation\u003c\/strong\u003e\u003cbr\u003eBy placing an order, you confirm that you are 18 years of age or older and are purchasing on behalf of a laboratory, organisation, or professional research activity.\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003cbr\u003eProduct Form: Lyophilised powder\u003cbr\u003ePurity: ≥98%\u003cbr\u003eQuantity: 10mg, 20mg, 40mg\u003cbr\u003ePackaging: Sterile sealed vial\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003cstrong\u003eLegal Use\u003c\/strong\u003e\u003cbr\u003eThis product is sold strictly for in-vitro research and laboratory use only. It is not a medicine, supplement, or cosmetic and must not be consumed, injected, or applied to humans or animals.\u003c\/p\u003e\n\u003cp\u003eSuitable for analytical testing, reference comparison and controlled peptide research.\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003cstrong\u003eStorage, Handling \u0026amp; Safety\u003c\/strong\u003e\u003cbr\u003eStore frozen at −20 °C for long-term stability. Short-term temperature fluctuations during shipping do not affect product integrity.\u003cbr\u003eProtect from heat, moisture, and direct light.\u003cbr\u003eProducts may present chemical hazards. Appropriate laboratory PPE, engineering controls, and disposal procedures must be followed at all times.\u003cbr\u003eFor laboratory research use only. Not for human or veterinary use.\u003c\/p\u003e","brand":"G11 Peptides","offers":[{"title":"10mg","offer_id":52583282606416,"sku":null,"price":23.99,"currency_code":"GBP","in_stock":true},{"title":"20mg","offer_id":53071233122640,"sku":null,"price":41.99,"currency_code":"GBP","in_stock":true},{"title":"40mg","offer_id":52573527408976,"sku":null,"price":55.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0924\/8266\/6832\/files\/MOTS-CVIAL.png?v=1768653095","url":"https:\/\/g11peptides.co.uk\/products\/mots-c","provider":"G11 Peptides","version":"1.0","type":"link"}