{"product_id":"pe-22-28","title":"PE-22-28 – 10mg (Lyophilised)","description":"\u003cp\u003e\u003cstrong\u003ePE-22-28 – 10mg (Lyophilised)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProduct \u0026amp; Research Profile\u003c\/strong\u003e\u003cbr\u003ePE-22-28 is a synthetic seven-amino-acid research peptide derived from spadin, a peptide associated with the TREK-1 potassium channel.\u003c\/p\u003e\n\u003cp\u003eTREK-1, also known as KCNK2, is a two-pore-domain potassium channel involved in regulating membrane potential, electrical excitability and cellular signalling. PE-22-28 is studied for its ability to inhibit TREK-1 activity, giving it a distinctive research profile within ion-channel and neurobiology research.\u003c\/p\u003e\n\u003cp\u003eBecause PE-22-28 is a shortened spadin-derived sequence, it is particularly useful for investigating how peptide size and structure influence channel interaction, binding behaviour and molecular stability. This makes it relevant to controlled studies of peptide–channel interactions, potassium-channel signalling, electrophysiological models and structure–activity relationships.\u003c\/p\u003e\n\u003cp\u003eIts defined short-chain structure also makes PE-22-28 suitable for analytical characterisation and comparative research alongside other spadin-derived and TREK-1-targeting compounds.\u003c\/p\u003e\n\u003cp\u003eSupplied as a lyophilised powder in sealed laboratory vials, PE-22-28 is available in a 10mg quantity for research and analytical applications.\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003cstrong\u003e18+ Purchase Confirmation\u003c\/strong\u003e\u003cbr\u003eBy placing an order, you confirm that you are 18 years of age or older and are purchasing on behalf of a laboratory, organisation, or professional research activity.\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003cstrong\u003eProduct Details\u003c\/strong\u003e\u003cbr\u003eProduct Form: Lyophilised powder\u003cbr\u003ePurity: ≥98%\u003cbr\u003eQuantity: 10mg\u003cbr\u003ePackaging: Sterile sealed vial\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003cstrong\u003eLegal Use\u003c\/strong\u003e\u003cbr\u003eThis product is sold strictly for in-vitro research and laboratory use only. It is not a medicine, supplement, or cosmetic and must not be consumed, injected, or applied to humans or animals.\u003c\/p\u003e\n\u003cp\u003eSuitable for analytical testing, reference comparison and controlled peptide research.\u003c\/p\u003e\n\u003chr\u003e\n\u003cp\u003e\u003cstrong\u003eStorage, Handling \u0026amp; Safety\u003c\/strong\u003e\u003cbr\u003eStore frozen at −20 °C for long-term stability. Short-term temperature fluctuations during shipping do not affect product integrity.\u003cbr\u003eProtect from heat, moisture, and direct light.\u003cbr\u003eProducts may present chemical hazards. Appropriate laboratory PPE, engineering controls, and disposal procedures must be followed at all times.\u003cbr\u003eFor laboratory research use only. Not for human or veterinary use.\u003c\/p\u003e","brand":"G11 Peptides","offers":[{"title":"Default Title","offer_id":52572233630032,"sku":null,"price":28.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0924\/8266\/6832\/files\/PE-22-28VIAL.png?v=1768692495","url":"https:\/\/g11peptides.co.uk\/products\/pe-22-28","provider":"G11 Peptides","version":"1.0","type":"link"}