PE-22-28 – 10mg (Lyophilised)

PE-22-28 – 10mg (Lyophilised)

Product & Research Profile
PE-22-28 is a synthetic seven-amino-acid research peptide derived from spadin, a peptide associated with the TREK-1 potassium channel.

TREK-1, also known as KCNK2, is a two-pore-domain potassium channel involved in regulating membrane potential, electrical excitability and cellular signalling. PE-22-28 is studied for its ability to inhibit TREK-1 activity, giving it a distinctive research profile within ion-channel and neurobiology research.

Because PE-22-28 is a shortened spadin-derived sequence, it is particularly useful for investigating how peptide size and structure influence channel interaction, binding behaviour and molecular stability. This makes it relevant to controlled studies of peptide–channel interactions, potassium-channel signalling, electrophysiological models and structure–activity relationships.

Its defined short-chain structure also makes PE-22-28 suitable for analytical characterisation and comparative research alongside other spadin-derived and TREK-1-targeting compounds.

Supplied as a lyophilised powder in sealed laboratory vials, PE-22-28 is available in a 10mg quantity for research and analytical applications.

18+ Purchase Confirmation
By placing an order, you confirm that you are 18 years of age or older and are purchasing on behalf of a laboratory, organisation, or professional research activity.

Product Details
Product Form: Lyophilised powder
Purity: ≥98%
Quantity: 10mg
Packaging: Sterile sealed vial

Legal Use
This product is sold strictly for in-vitro research and laboratory use only. It is not a medicine, supplement, or cosmetic and must not be consumed, injected, or applied to humans or animals.

Suitable for analytical testing, reference comparison and controlled peptide research.

Storage, Handling & Safety
Store frozen at −20 °C for long-term stability. Short-term temperature fluctuations during shipping do not affect product integrity.
Protect from heat, moisture, and direct light.
Products may present chemical hazards. Appropriate laboratory PPE, engineering controls, and disposal procedures must be followed at all times.
For laboratory research use only. Not for human or veterinary use.